Energy and Matter at the Origins of Life by Nick Lane | Santa Fe Institute

Energy and Matter at the Origins of Life by Nick Lane | Santa Fe Institute
Energy and Matter at the Origin of Life by Nick Lane (Santa Fe Institute Community Event (YouTube))

All living things are made of cells, and all cells are powered by electrochemical charges across thin lipid membranes — the ‘proton motive force.’ We know how these electrical charges are generated by protein machines at virtually atomic resolution, but we know very little about how membrane bioenergetics first arose. By tracking back cellular evolution to the last universal common ancestor and beyond, scientist Nick Lane argues that geologically sustained electrochemical charges across semiconducting barriers were central to both energy flow and the formation of new organic matter — growth — at the very origin of life.

Dr. Lane is a professor of evolutionary biochemistry in the Department of Genetics, Evolution and Environment at University College London. His research focuses on how energy flow constrains evolution from the origin of life to the traits of complex multicellular organisms. He is a co-director of the new Centre for Life’s Origins and Evolution (CLOE) at UCL, and author of four celebrated books on life’s origins and evolution. His work has been recognized by the Biochemical Society Award in 2015 and the Royal Society Michael Faraday Prize in 2016.

h/t Santa Fe Institute

Energy and Matter at the Origins of Life by Nick Lane | Santa Fe Institute was originally published on Chris Aldrich


Valerie Alexander on How Women Can Succeed in the Workplace (Despite Having “Female Brains”)

This morning, at the Friday morning coffee meetup of Innovate Pasadena held at Cross Campus, I saw one of the singularly best and most valuable talks I’ve heard in a long time. Many of these types of speakers, while engaging or even entertaining, are telling the same tired stories and at best you learn one sentence’s worth of value. Definitively not the case this morning!!!

How Women Can Succeed in the Workplace (Despite Having “Female Brains”) by Valerie Alexander

Entitled How Women Can Succeed in the Workplace (Despite Having “Female Brains”) writer and speaker Valerie Alexander presented a brief discussion of human evolutionary history (a topic I’ve studied closely for several decades) that featured the difference in development of male and female human brains. Based on this and with a clearer picture of what broadly differentiates the sexes, Valerie then gave a multitude of highly relate-able examples from her professional life highlighting how women can simply take back control in the workplace to not only better succeed for themselves, but to also help their companies see their true value and succeed simultaneously.

Further, she also included some simple and very actionable advice (for men and women) to be able to make a better space within corporations so that they’re able to extract more of the value women bring to the workplace. Hint: Women bring a HUGE amount of value, and a majority of companies are not only undervaluing it, but they are literally throwing it away.

Not only were the messages tremendously valuable and imminently actionable by both women AND men, but she delivered it with fantastic confidence, grace, wit, charm, and warmth. In fact, I’d say it was not only strikingly informative, but it was also very entertaining. If you’re in the corporate space and looking to turn around your antediluvian or even pre-historic work culture (I’m looking ominously at you Uber and similar Silicon Valley brogrammer cultures), then jump in line as quickly as you can to book up what I can only expect is the diminishing time in her speaking and travel schedule.

Innovate Pasadena recorded the talk and I’ll try to post it here as soon as it’s available. Until then I will highly recommend purchasing her book How Women Can Succeed in the Workplace (Despite Having “Female Brains”), which I’m sure has not only the content of her lecture, but assuredly includes a whole lot more detail and additional examples than one could fit into such a short time frame. I also suspect it’s the type of book one would want to refer back to frequently as well. I’ve already got a half a dozen copies of it on their way to me to share with friends and family. I’m willing to make a substantial bet that for uncovering inherent value, this book and her overall message will eventually stand in the pantheon of texts and work of those like those of Frederick Winslow Taylor, Lillian Gilbreth, Frank Gilbreth, Dale Carnegie, Napoleon Hill, J.M. Juran, and W. Edwards Deming.

Psst… If the good folks at TED need some fantastic content, I saw a shortened 25 minute version of her hour-long talk. It could be tightened a hair for content and length, but it’s got exactly the tone, tempo and has the high level of presentation skills for which you’re known. Most importantly, it’s definitively an “Idea worth spreading.”

Innovate Pasadena has finally uploaded a copy of the video of Valerie Alexander’s talk:

Valerie Alexander on How Women Can Succeed in the Workplace (Despite Having “Female Brains”) was originally published on Chris Aldrich

🔖 Human Evolution: Our Brains and Behavior by Robin Dunbar (Oxford University Press) marked as want to read.
Official release date: November 1, 2016
09/14/16: downloaded a review copy via NetGalley


The story of human evolution has fascinated us like no other: we seem to have an insatiable curiosity about who we are and where we have come from. Yet studying the “stones and bones” skirts around what is perhaps the realest, and most relatable, story of human evolution – the social and cognitive changes that gave rise to modern humans.

In Human Evolution: Our Brains and Behavior, Robin Dunbar appeals to the human aspects of every reader, as subjects of mating, friendship, and community are discussed from an evolutionary psychology perspective. With a table of contents ranging from prehistoric times to modern days, Human Evolution focuses on an aspect of evolution that has typically been overshadowed by the archaeological record: the biological, neurological, and genetic changes that occurred with each “transition” in the evolutionary narrative. Dunbar’s interdisciplinary approach – inspired by his background as both an anthropologist and accomplished psychologist – brings the reader into all aspects of the evolutionary process, which he describes as the “jigsaw puzzle” of evolution that he and the reader will help solve. In doing so, the book carefully maps out each stage of the evolutionary process, from anatomical changes such as bipedalism and increase in brain size, to cognitive and behavioral changes, such as the ability to cook, laugh, and use language to form communities through religion and story-telling. Most importantly and interestingly, Dunbar hypothesizes the order in which these evolutionary changes occurred-conclusions that are reached with the “time budget model” theory that Dunbar himself coined. As definitive as the “stones and bones” are for the hard dates of archaeological evidence, this book explores far more complex psychological questions that require a degree of intellectual speculation: What does it really mean to be human (as opposed to being an ape), and how did we come to be that way?

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🔖 Human Evolution: Our Brains and Behavior by Robin Dunbar (Oxford University Press) was originally published on Chris Aldrich | Boffo Socko

NIMBioS Tutorial: Evolutionary Quantitative Genetics 2016

NIMBioS Tutorial: Evolutionary Quantitative Genetics 2016 by NIMBioS (

This tutorial will review the basics of theory in the field of evolutionary quantitative genetics and its connections to evolution observed at various time scales. Quantitative genetics deals with the inheritance of measurements of traits that are affected by many genes. Quantitative genetic theory for natural populations was developed considerably in the period from 1970 to 1990 and up to the present, and it has been applied to a wide range of phenomena including the evolution of differences between the sexes, sexual preferences, life history traits, plasticity of traits, as well as the evolution of body size and other morphological measurements. Textbooks have not kept pace with these developments, and currently few universities offer courses in this subject aimed at evolutionary biologists. There is a need for evolutionary biologists to understand this field because of the ability to collect large amounts of data by computer, the development of statistical methods for changes of traits on evolutionary trees and for changes in a single species through time, and the realization that quantitative characters will not soon be fully explained by genomics. This tutorial aims to fill this need by reviewing basic aspects of theory and illustrating how that theory can be tested with data, both from single species and with multiple-species phylogenies. Participants will learn to use R, an open-source statistical programming language, to build and test evolutionary models. The intended participants for this tutorial are graduate students, postdocs, and junior faculty members in evolutionary biology.

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NIMBioS Tutorial: Evolutionary Quantitative Genetics 2016 was originally published on Chris Aldrich | Boffo Socko